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23-Oct-2016 13:35

This condition occurs only in females, as there are no Y chromosomes present.

Tetrasomy X was first described in 1961, and since then approximately 100 cases have been reported worldwide.

Approximately 60 affected females have been described in the medical literature.

Delays in motor development are also present, with walking ages ranging from 16 months to 4.5 years.

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Delays in motor development are also present, with walking ages ranging from 16 months to 4.5 years.

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You only have permission to enter this Website if you are at least 18 years of age, or at least the age of majority in the jurisdiction where you reside or from which you access this Website.

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About 50% of patients undergo puberty normally, whereas the other 50% experiences no puberty, partial puberty without secondary sexual characteristics, or complete puberty with menstrual irregularities and/or early menopause (possibly as early as the teens).